Description

Buy Pramiracetam | Pramiracetam Review

(bulk powder)
(Pramistar 10x600mg)

Pramiracetam (N-[2-(Diisopropylamino)ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide) salso known as: Remen, Neupramir or Pramistar, was discovered and developed by Parke-Davis in the 1970s . This racetam exhibits a remarkable oral bioavailability, it is more potent than piracetam. Pramiracetam optimizes brain performance and provides marked cognitive improvement, particularly regarding memory formation and retrieval. It has been also extensively studied as a potential treatment for cognitive problems and memory loss associated with Alzheimer’s disease and brain injury. Pramiracetam has a very specific method of action in hippocampal Acetylcholine turnover.  Unlike Aniracetam and Noopept, Pramiracetam does not seem to influence the dopaminergic or serotonin (5HT) receptor sites. Is well tolerated, without side effects. Typical Pramiracetam dosage is about 300-600mg.  Currentny we have a bulk powder product and oryginal russian Pramistar (blisters 10x600mg).

Pramiracetam Pharmacokinetics

Oral absorption of Pramiracetam is moderately fast, maximum plasma concentrations (3-9 ug/ml) is reached 2,5h after administration of 400-1600mg.

Pramiracetam Mechanisms of Action

Pramiracetam enhances High Affinity Choline Uptake in hippocampus in dose dependent fashion,  this effects lasts up to 24 hours. Choline is acetylcholine (neurotransmitter ) precursor cruitial for optimal neurotransmission. It doen’t interact with other neurotransmitters: noradrenaline, dopamine and 5-hydroksytryptamine (serotonine). It also was shown that Pramiracetam  increases cerebral blood flow.  Busers buy Pramiracetam for its benefits:

Pramiracetam Benefits

Improved Memory – Because it stimulates the hippocampus, the part of the brain primarily responsible for the creation of new memories, pramiracetam is known as a very powerful memory enhancer.

Expanded Learning Capacity – Users report that pramiracetam makes learning faster, easier, and more enjoyable. This can be explained at least in part by pramiracetam’s facilitation of greater neuroplasticity.

Memory Repair – In limited clinical trials, pramiracetam has been shown to be an effective treatment for memory loss and other cognitive problems

Pramiracetam Dosage 300-600mg

CAS 68497-62-1

Formula C₁₄H₂₇N₃O₂

Mass 69.383 Da

Synonyms Pramistar, Remen, Neupramir

Half-life 2-8h

Bioavailability 100%

1. Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.

2. Pramiracetam effects on scopolamine-induced amnesia in healthy volunteers.

3. Pharmacokinetics of pramiracetam in healthy volunteers after oral administration.

4. A new one-trial test for neurobiological studies of memory in rats. II: Effects of piracetam and pramiracetam.