Description

Buy Piracetam | Piracetam Reviews

(bulk powder)

Piracetam (2-oxo-1-pyrrolidine-acetamide), the most common of the nootropic drugs, is a cyclic derivative of gamma-aminobutyric acid. The treatment with piracetam improves learning, memory, brain metabolism, and capacity. Piracetam has been shown to alter the physical properties of the plasma membrane by increasing its fluidity and by protecting the cell against hypoxia. The interaction of this molecule with the membrane phospholipids restores membrane fluidity and could explain the efficacy of piracetam in various disorders ranging from dementia and vertigo to myoclonus and stroke. It is the first representative of the „nootropic” drugs. The term nootropic comes from a Greek words meaning  „acting on the mind”. Piracetam was synthesized by Giurgea in UCB Laboratories In Belgium. It has been in clinical use since 1972. Piracetam enhances cognition and also enhances memory and learning. When piracetam is taken with choline, there is a synergistic effect that causes a greater improvement in memory. It has been also shown that piracetam protect neurons from heroin-induced apoptosis. Typical Piracetam dosage is about 800-1200mg.

Piracetam Pharmacokinetics

Piracetam is absorbed  very well (oral administration) with a  bioavailability of almost 100% and reaches maximum plasma concentration 50ug/ml after 30-40 minutes (2g dose). Drug is excreted in unchanged form in the urine and completely eliminated after 30 hours, crosses blood brain barrier slowly, because of its high hydrophilicity.

Piracetam Mechanisms of Action

Mechanism of action is unclear, some researchers suggested that drug enhances energy metabolism and oxygen utilization in the brain by interacting with ion channels/transporters in central nervous system.

Users buy Piracetam powder for its benefits:

Piracetam Benefits

• Memory Improvement

• Age-related Neuroprotection

• Increased Sensory Perception

Piracetam dosage 800-1200mg

CAS 7491-74-9

Formula C₆H₁₀N₂O₂

Mass 142.156 Da

Synonyms Nootropil, Nootrop, Nootropyl, Geratam

Half-life 4-5h

Bioavailability 100%

References:

1. Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.

2. Piracetam FAQ (EROWID)

3. Study of Brāhmī Ghṛta and piracetam in amnesia.

4. Piracetam treatment in patients with cognitive impairment.

5. Piracetam improves children’s memory after general anaesthesia.

6. Piracetam improves cognitive deficits caused by chronic cerebral hypoperfusion in rats.

7. Effects of piracetam on the cognitive functions verified by electrophysiologic methods.

8. Clinical efficacy of piracetam in cognitive impairment: a meta-analysis.

9. The effects of piracetam on heroin-induced CPP and neuronal apoptosis in rats.