Description

Buy Nefiracetam

(bulk powder)

Nefiracetam belongs to the family of racetams.  This cogntive enhancer and was first developed and tested as a beneficial supplement for Alzheimer’s disease, epilepsy and dementia. Although it has a structure similar to Aniracetam it was originally derived from Piracetam. Limited human clinical evidence exists, but it appears that Nefiracetam is able to increase memory formation when taken daily over a prolonged period of time. It is known to open calcium channels which prolongs its presence in the activated neuron before increasing signaling of acetylcholine and glutamate at the synapse. This ability gives Nefiracetam nootropic value. Typical Nefiracetam dosage  is about 150 mg. 

Nefiracetam Mechanisms of Action

Nefiracetam potentiates nicotinic acetylocholine receptors and opens calcium channels.

Nefiracetam Pharmacokinetics

In humans, its concentration in blood reaches maximum after 2 hours after oral administration, with half-life of 3-5 hours. Users buy Nefiracetam for its benefits:

Nefiracetam Benefits

• Promotes brain health & communication

• Supports memory, reasoning & cognition

• Boosts focus, mental clarity & attention

Nefiracetam Dosage  150 mg     

CAS 77191-36-7

Formula C₁₄H₁₈N₂O₂

Mass 246.305 Da

Half-life 3-5h

References:

1. Single- and multiple-dose pharmacokinetics of nefiracetam, a new nootropic agent, in healthy volunteers.

2. Nefiracetam. Daiichi Seiyaku.

3. The cognition-enhancer nefiracetam is protective in BDNF-independent neuronal cell death under the serum-free condition.

4. Cellular mechanism of action of cognitive enhancers: effects of nefiracetam on neuronal Ca2+ channels.

5. Nefiracetam facilitates hippocampal neurotransmission by a mechanism independent of the piracetam and aniracetam action.

6. Improvement of depressive behaviors by nefiracetam is associated with activation of CaM kinases in olfactory bulbectomized mice.